Dr. Amy Johnson on Research Into Acalabrutinib as a Treatment for CLL
Amy Johnson, PhD, discusses the overall high response rates in patients with chronic lymphocytic leukemia (CLL) to a new novel bruton tyrosine kinase (BTK) inhibitor called acalabrutinib (ACP-196).
Amy Johnson, PhD, associate professor, Hematology, Ohio State University, discusses the overall high response rates in patients with chronic lymphocytic leukemia (CLL) to a new novel bruton tyrosine kinase (BTK) inhibitor called acalabrutinib (ACP-196). Acalabrutinib is a selective, irreversible BTK inhibitor designed to improve both the safety and efficacy of BTK inhibitors in CLL.
Johnson says there is currently neither a subtype of patient with CLL that benefits from acalabrutinib, nor is there a subtype that suffers from the treatment.
Evaluating Role of Loncastuximab in Third-Line DLBCL After CAR T
May 7th 2025During a live event, Krish Patel, MD, discussed barriers to using bispecific T-cell engagers and practical considerations of using loncastuximab in a patient with relapsed diffuse large B-cell lymphoma who had prior CAR T-cell therapy.
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Examining the Non-Hodgkin Lymphoma Treatment Paradigm
July 15th 2022In season 3, episode 6 of Targeted Talks, Yazan Samhouri, MD, discusses the exciting new agents for the treatment of non-Hodgkin lymphoma, the clinical trials that support their use, and hopes for the future of treatment.
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Prior Pelvic Radiation Linked to Higher Complications After Bladder Cancer Surgery
April 30th 2025Bladder cancer patients undergoing radical cystectomy after pelvic radiotherapy showed increased risks of rectal injury, readmission, sepsis, and surgical-site infections compared with primary surgery.
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