The Clinical Utility of Ki67 in Breast Cancer

Torsten O. Nielsen, MD, PhD, FRCPC

Torsten O. Nielsen, MD, PhD, FRCPC, professor, pathology, University of British Columbia, discusses Ki67 in breast cancer.

Torsten O. Nielsen, MD, PhD, FRCPC, professor, pathology, University of British Columbia, discusses Ki67 in breast cancer.

In his presentation at the 12th International Congress on the Future of Breast Cancer from July 18-20, 2013, in Huntington Beach, CA, Nielsen discussed the clinical utility of the Ki67 protein in breast cancer.

Clinical Pearls

Ki67 is a convenient immunohistochemical tool for measuring proliferation, which is a critical factor in breast cancer, as well as in other cancers. The nature of the Ki67 protein, with its repeated element, is beneficial for an antigen antibody interaction. This produces the best, cheapest, and most widely available immunohistochemistry to measure proliferation on standard paraffin biopsy specimens.

  • Ki67 is a convenient immunohistochemical tool for measuring proliferation
  • The nature of the Ki67 protein is very good for an antigen antibody interaction