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Opinion|Videos|January 13, 2025

Key Considerations for the Evolving Treatment Landscape for Relapsed/Refractory Follicular Lymphoma

Author(s)Juan Pablo Alderuccio, MD

A panelist discusses how various antibody-drug conjugates, including polatuzumab vedotin, pinatuzumab vedotin, and loncastuximab, have been studied in combination with rituximab for relapsed/refractory follicular lymphoma. Recent data from ASH 2024 highlight important patient considerations for these treatment approaches.

Episodes in this series

EP. 1 An Overview of the Current Treatment Landscape for R/R FL

EP. 1 An Overview of the Current Treatment Landscape for R/R FL

EP. 2 Exploring ADC/Antibody Combination Therapies in Development for R/R FL

EP. 2 Exploring ADC/Antibody Combination Therapies in Development for R/R FL

EP. 3 An Investigator-Initiated Study of Loncastuximab Tesirine Plus Rituximab for the Treatment of R/R FL

EP. 3 An Investigator-Initiated Study of Loncastuximab Tesirine Plus Rituximab for the Treatment of R/R FL

EP. 4 Recent Safety and Efficacy Updates from the Investigator Initiated Study of Loncastuximab tesirine + Rituximab for the Treatment of R/R FL

EP. 4 Recent Safety and Efficacy Updates from the Investigator Initiated Study of Loncastuximab tesirine + Rituximab for the Treatment of R/R FL

$EP. 5 Key Considerations for the Evolving Treatment Landscape for Relapsed/Refractory Follicular Lymphoma$

EP. 5 Key Considerations for the Evolving Treatment Landscape for Relapsed/Refractory Follicular Lymphoma

$EP. 6 Future Perspectives on the Relapsed/Refractory Follicular Lymphoma Treatment Landscape$

EP. 6 Future Perspectives on the Relapsed/Refractory Follicular Lymphoma Treatment Landscape

Video content above is prompted by the following:

Other antibody-drug conjugates have been examined in the relapsed/refractory follicular lymphoma (R/R FL) space in combination with rituximab.
Polatuzumab vedotin + rituximab and pinatuzumab vedotin + rituximab. In the R/R FL population, how do these agents perform?
Given the data update from Alderuccio et al. ASH 2024, comment on how loncastuximab + rituximab could play a role in the treatment landscape for R/R FL. What patient considerations are critical to note?

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