Improving the Treatment of Locally Advanced Pancreatic Cancer
Video
Improving the Treatment of Locally Advanced Pancreatic Cancer
May 2017
A 64-year-old female was diagnosed with locally advanced pancreatic adenocarcinoma and referred for consultation at a high-volume center
CT with contrast showed a 2.8-cm mass in the pancreatic body, invading the common hepatic, celiac, and splenic arteries, with abutment more than 180° to the superior mesenteric artery (SMA) but no encasement
Staging laparoscopy showed no distant metastasis; peritoneal washing cytology showed no malignant cells
She received FOLFIRINOX followed by capecitabine and concurrent RT
December 2017
Six months after the initial treatment, the tumor size had decreased to 1.2 cm, and abutment to the main artery was diminished but still detectable
She underwent distal pancreatectomy with celiac artery resection
Histopathology showed fibrous changes around the celiac artery; Evans grade IIb
No evidence of residual tumor at the periphery; R0