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Opinion|Videos|December 13, 2024

MonumenTAL-1: Data Updates of Talquetamab, a GPRC5D-Directed Bispecific Antibody for RRMM

Author(s)Binod Dhakal, MD, MS

Panelist discusses how the MonumenTAL-1 study led to the approval of talquetamab in patients with 4 or more prior lines of therapy, and the initial response rate was 70%. There were also several toxicities associated with MonumenTAL-1, including oral, nail, and skin toxicities.

Episodes in this series

1 expert in this video

EP. 1 Patient Profile: A 72-Year-Old Man With RRMM

1 expert in this video

EP. 2 Overview of Bispecifics for R/R Multiple Myeloma

1 expert in this video

EP. 3 MonumenTAL-1: Data Updates of Talquetamab, a GPRC5D-Directed Bispecific Antibody for RRMM

1 expert in this video

EP. 4 Talquetamab Step-Up Dosing Strategies and CRS Monitoring

1 expert in this video

EP. 5 Additional Toxicities in GPRC5D-Directed Bispecifics for RRMM

1 expert in this video

EP. 6 Data and Treatment Considerations for BCMA-Directed Bispecifics in RRMM

1 expert in this video

EP. 7 The Future of Bispecific Therapy for R/R Multiple Myeloma

Video content above is prompted by the following:

How does the long-term efficacy and safety data update from MonumenTAL-1 further inform the treatment decision between BiTEs for RRMM patients?

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