Dr. Reuben S. Harris on APOBEC3B as a Possible Treatment Variable in Breast Cancer

APOBEC3B was investigated in a retrospective study of a cohort available for analysis from a Dutch study. Results shows patients with high levels of APOBEC3B had much worse outcomes compared to those with low levels.

Reuben S. Harris, PhD, investigator, Howard Hughes Medical Institute, professor, Department of Biochemistry, Molecular Biology, and Biophysics at the University of Minnesota College of Biological Sciences, discusses the need for further analysis of APOBEC3B, an anti-viral enzyme, as a possible treatment variable in breast cancer.

APOBEC3B was investigated in a retrospective study of a cohort available for analysis from a Dutch study. Harris looked at APOBEC3B expression and stratified data for recurrent disease outcome overtime. Results shows patients with high levels of APOBEC3B had much worse outcomes compared to those with low levels.