The Treatment of Elderly Patients With Lymphoma

Clinical Pearls

Andre Goy, MD, chairman, director, and chief of the Lymphoma Division at the John Theurer Cancer Center, discusses the treatment of elderly patients with lymphoma.

• Data from the GELA trial were impressive: Benefit was seen regardless of age with the R-CHOP combination
• Elderly patients typically have more aggressive and higher risk disease
• The standard of care is R-CHOP-21, though patients in good condition with high-risk disease can tolerate R-EPOCH
• Frail patients should be treated with mini-CHOP
• The incidence of large cell lymphoma in the elderly has increased 500% in the last 10 years, creating a need for better therapeutic options