Husain Evaluates Real-World Evidence for Immunotherapy in Stage III NSCLC
February 24th 2024During a Community Case Forum event in partnership with the Texas Society of Clinical Oncology, Hatim Husain, MD, explained the significance of the PACIFIC trial and its real-world counterpart PACIFIC-R looking at the use of durvalumab after chemotherapy and radiation in patients with unresectable stage III non–small cell lung cancer.
Risk Groups Vital to Interpreting Results of RCC Immunotherapy Trials
February 21st 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Robert J. Motzer, MD, examined the impact of the CheckMate 214 and CheckMate 9ER trials of nivolumab/ipilimumab and nivolumab/cabozantinib in patients with advanced renal cell carcinoma. This is the first of 2 articles based on this event.
O’Shaughnessy Explores Mechanisms of Resistance to CDK4/6 Inhibition in ER+ Breast Cancer
February 21st 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Joyce O'Shaughnessy, MD, reviewed the current state of CDK4/6 inhibitor therapy for patients with advanced estrogen-receptor positive breast cancer.
Velcheti Addresses Promising Data with Repotrectinib in ROS1+ NSCLC
February 20th 2024In the first article of a 2-part series, Vamsidhar Velcheti, MD, MBA, discussed why patients with lung cancer may experience dizziness with repotrectinib and why the efficacy data behind this therapy are considered impressive.
Comprehensive Molecular Testing Needed for Frontline NSCLC Treatment
February 19th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Misako Nagasaka, MD, PhD, held a discussion on the use of biomarker testing in patients with advanced non–small cell lung cancer. This is the first of 2 articles based on this event.
Bell Discusses Options for a Patient With MSI-High, dMMR Endometrial Cancer
February 19th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Maria Bell, MD, MPH, MBA, moderated a discussion on biomarker testing and treatment for a patient with extensive, well-differentiated, grade 1 endometrioid adenocarcinoma.
What is the Best Dose of Lenalidomide? Lunning Provides His Analysis in R/R DLBCL
February 16th 2024In the second part of a 2-article series, Matthew A. Lunning, DO, FACP, leads a discussion on how to best manage toxicities from tafasitamab and lenalidomide for patients with relapsed/refractory diffuse large B-cell lymphoma.
Risk Stratification Influences Choice of Frontline IO/TKI Regimen in mRCC
February 13th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Rana McKay, MD, moderated a discussion on what role risk stratification plays in selecting frontline therapy for a patient with metastatic renal cell carcinoma. This is the first of 2 articles based on this event.
Peer Discussion Addresses Challenges in Recurrent Endometrial Cancer Treatment
February 13th 2024During an in-person Community Case Forum event in New Jersey, Thomas Herzog, MD, and various participants discussed their approaches to molecular testing and treatment for patients with recurrent endometrial cancer.
Analyzing The Use of Elacestrant in ESR1+ Advanced Breast Cancer
February 12th 2024In the second article of a 2-part series, Komal Jhaveri, MD, leads a discussion on the considerations physicians must have when looking to give elacestrant to patients with estrogen receptor–positive, HER2 negative metastatic breast cancer.
Lipson Considers Tolerability When Selecting Immunotherapy for Metastatic Melanoma
February 11th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Evan J. Lipson, MD, and participants discussed tolerability factors that could influence the choice of frontline immunotherapy regimen for a patient with metastatic melanoma.
Shahin Analyzes Benefits of Individualized Dosing With PARP Inhibitors in Advanced Ovarian Cancer
February 10th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Mark S. Shahin, MD, discussed with participants how they use the individualized dose of niraparib and manage adverse events in patients with advanced ovarian cancer.
Assessing the Durability, Tolerability of Loncastuximab in R/R DLBCL
February 7th 2024In the second part of a 2-article series, Matthew Matasar, MD, MS, discusses long-term follow up data from the LOTIS-2 trial and how these data show the durability and tolerability of loncastuximab for patients with relapsed/refractory diffuse large B-cell lymphoma.
Tolerability Concerns Influence Use of Lenvatinib/Everolimus Vs Tivozanib in RCC
February 6th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Sumanta K. Pal, MD, and participants explored the third-line treatment options for a patient with advanced renal cell carcinoma. This is the second of 2 articles based on this event.
Unanswered Questions About Adjuvant Osimertinib in Resectable NSCLC
February 1st 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Balazs Halmos, MD, discussed with participants how they interpret the ADAURA trial and the approach to adjuvant targeted therapy in non–small cell lung cancer This is the second of two articles based on this event.
Breaking Down Considerations for Tafasitamab/Lenalidomide in DLBCL
January 24th 2024In the first part of a 2-article series, Matthew A. Lunning, DO, FACP, takes into consideration the perspectives of his peers on the use of tafasitamab and lenalidomide for patients with relapsed/refractory diffuse large B-cell lymphoma.
Peers Discuss Impressions of Tivozanib’s Role as Third-Line RCC Therapy
January 23rd 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Sumanta K. Pal, MD, discussed the case of an older patient with metastatic renal cell carcinoma who had recurrent disease after receiving axitinib and pembrolizumb, then single-agent cabozantinib. This is the first of 2 articles based on this event.
Different Approaches Available for Identifying and Managing Chronic GVHD
January 22nd 2024In the first article of a 2-part series, Lori Muffly, MD, MS, discusses with a panel of physicians what their approach is to identifying patients with severe chronic graft-versus-host-disease and how they treat them in conjunction with the transplant team.
Elranatamab Shows Efficacy of BCMA-Targeted Therapy in Multiple Myeloma
January 18th 2024During a Targeted Oncology™ Case-Based Roundtable™ event, Mansi R. Shah, MD, discussed the impact of the MagnetisMM-1 and MagnetisMM-3 trials of elranatamab in patients with relapsed/refractory multiple myeloma. This is the second of 2 articles based on this event.