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Leukemia

A complete response letter has been issued to Daiichi Sankyo from the FDA, alerting the company to the reasons why the new drug application for quizartinib as a treatment of adult patients with relapsed/refractory <em>FLT3</em>-ITD–positive acute myeloid leukemia would not be approved.








Patients with early-stage, asymptomatic, newly diagnosed chronic lymphocytic leukemia showed improved survival outcomes with ibrutinib monotherapy compared with placebo, according to results from phase III CLL12 study presented at the 2019 European Hematology Association Congress.<br />

In an interview with <em>Targeted Oncology</em>, Naval G. Daver, MD, discussed the possibility of combination therapy in patients with AML. He highlights some of the most recent data to come out for this patient population, including for those harboring a <em>TP53</em> or <em>FLT3</em> mutation.


























































