May 8th 2024
During a Case-Based Roundtable® event, Lori A. Leslie, MD, discussed Bruton tyrosine kinase inhibition options for a patient with relapsed/refractory chronic lymphocytic leukemia in the first article of a 2-part series.
Community Practice Connections™: Real-World Applications of Novel Therapies Across TNBC and Addressing Disparities in Care
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6th Annual Precision Medicine Symposium: An Illustrated Tumor Board
October 18-19, 2024
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Advances in TNBC: Communicating with Your Patients About Clinical Trial Awareness and Treatment Concerns to Improve Clinical Outcomes
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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Memory T Cells May Predict Response to CAR T-Cell Therapy in CLL
May 4th 2018Results from a recent study conducted at the University of Pennsylvania may demonstrate why some patients with chronic lymphocytic leukemia are resistant to tisagenlecleucel, while potentially providing a pathway to enhance patient response.
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Bendamustine/Rituximab is an Effective Salvage Therapy in CLL
May 2nd 2018The combination of bendamustine and rituximab induced a 12-month progression-free survival of 78.6% for patients with chronic lymphocytic leukemia, suggesting that the combination is an effective first salvage regimen.
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A Look Back at FDA News in the Month of April
May 1st 2018The FDA approved several indications throughout the month of April 2018. A number of drugs were granted priority review and Fast Track designation. The FDA also halted all clinical trials using tazemetostat as treatment, and new initiatives were introduced to help ease the development of genetic and genomic-based tests. Check out our list of all FDA happenings from April 2018.
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Voxtalisib Shows Promising Activity in Follicular Lymphoma
April 24th 2018Voxtalisib (XL765) monotherapy induced objective responses in 41.3% of patients with follicular lymphoma, but displayed minimal efficacy in patients with other lymphomas, according to results from a phase II trial of patients with relapsed or refractory lymphoma or chronic lymphocytic leukemia that were recently published in the Lancet Haematology.
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Targeted Oncology To Launch Virtual Tumor Board
April 23rd 2018<em>Targeted Oncology</em>™, a print and digital resource that offers content and expert opinions on precision medicine in oncology, will launch the first Expert Perspective: Virtual Tumor Board on April 30. The Virtual Tumor Board is a video-editorial board discussion that features key opinion leaders from a specific oncological field.
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Venetoclax Shows Promise as Salvage Therapy in CLL
April 18th 2018Venetoclax induced a response in two-thirds of patients with relapsed/refractory chronic lymphocytic leukemia who had progressed after receiving prior therapy with idelalisib, according to findings of a phase II study recently published in <em>Blood</em>.
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Selecting Patients for Treatment With Ibrutinib in CLL
April 14th 2018Jacqueline C. Barrientos, MD, associate professor of the Karches Center for Oncology Research at the Feinstein Institute for Medical Research, discusses which types of patients with chronic lymphocytic leukemia are the best candidates for treatment with ibrutinib
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Triplet Combination of Ibrutinib, Venetoclax, and Obinutuzumab Effective as Initial CLL Treatment
April 11th 2018According to preliminary results of a phase II trial, the combination of obinutuzumab (Gazyva), ibrutinib (Imbruvica), and venetoclax (Venclexta) is a safe initial therapy for treatment-naïve patients with chronic lymphocytic leukemia (CLL).
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Expert Discusses Novel Treatment Options for Relapsed/Refractory CLL
April 10th 2018According to Neil E. Kay, MD, novel agents, such as ibrutinib (Imbruvica), venetoclax (Venclexta), idelalisib (Zydelig), and acalabrutinib (Calquence), are revolutionizing treatment for patients with chronic lymphocytic leukemia. However, the best way to sequence these agents to maximize the benefit to patients is still unclear.
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