Treating High-Risk Multiple Myeloma

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Treating High-Risk Multiple Myeloma

  • A 74-year-old woman was admitted to the ICU with pneumococcal bacteremia. She complained of recent severe fatigue, loss of appetite, nausea
  • History: chronic HTN, aortic insufficiency, diabetes mellitus
  • X-ray of the pelvis showed numerous lytic lesions in the ilium and a large lesion in the right proximal femur
  • MRI confirmed a 9-mm lesion in the right femoral head and numerous bilateral T1 hypointense and T2 hyperintense lesions in both iliac region
  • Laboratory results:
    • Hb, 8.3 g/dL
    • Ca2+16.35 mg/dL
    • Creatinine, 1.0 mg/dL
    • Creatinine clearance, 59 mL/min
    • M-protein, 1.6 g/dL
    • B2M, 4.9 mcg/mL
    • SFLC, kappa, 150 mg/L
  • Bone marrow biopsy, 70% plasma cells
  • Molecular testing, t(4;14)
  • ECOG 2
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Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
Sham Mailankody, MBBS, an expert on multiple myeloma
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