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Opinion|Videos|July 29, 2024

COMMANDS Trial: Study Design, Patient Population, and Results

Author(s)Guillermo Garcia-Manero, MD

Guillermo Garcia-Manero, MD, reviews recent results from the COMMANDS study investigating luspatercept versus epoetin alfa in patients with ESA-naïve, transfusion dependent LR-MDS.

Episodes in this series

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 1 Overview of Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 2 Standard-of-Care Treatment for Patients with LR-MDS

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 3 Erythroid Maturating Agents (EMAs) for Frontline or Second-Line Treatment of Anemia in LR-MDS

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 4 COMMANDS Trial: Study Design, Patient Population, and Results

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 5 Classification Changes Impacting the Treatment of LR-MDS

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 6 Dose Escalation of Luspatercept on Trial and Real-World Data

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 7 Adverse Events with EMAs: Luspatercept

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 8 Current Approach for Treating Anemia in LR-MDS

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 9 Future Treatment for Anemia of LR-MDS

Guillermo Garcia-Manero, MD, an expert on MDS

EP. 10 Clinical Pearls for Community Oncologist Treating LR-MDS

Video content above is prompted by the following:

Please discuss the latest results from the COMMANDS study, evaluating luspatercept versus epoetin alfa in patients with erythropoiesis-stimulating agent-naïve (ESA-naïve), transfusion dependent LR-MDS.
- Please briefly discuss the study design and patient population for COMMANDS.
- What were the key efficacy results from the COMMANDS study?

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