Opinion|Videos|April 11, 2025

Disease Progression in DLBCL: Management Strategies and Quality-of-Life Considerations

Author(s)Gilles Salles, MD, PhD, Matthew A. Lunning, DO, FACP

Experts discuss how disease progression impacts patients with diffuse large B-cell lymphoma (DLBCL) and strategies for managing progressive disease based on first-line therapy selection, incorporating insights from the POLARIX 5-year subsequent treatment data and highlighting quality-of-life considerations that influence treatment decisions.

Episodes in this series

EP. 1 Advances in DLBCL Management: Long-Term Treatment Outcomes

EP. 1 Advances in DLBCL Management: Long-Term Treatment Outcomes

EP. 2 Long-Term Outcomes and Treatment Guidelines in DLBCL Management

EP. 2 Long-Term Outcomes and Treatment Guidelines in DLBCL Management

EP. 3 Evolving Treatment Strategies in DLBCL: Real-World Clinical Experience

EP. 3 Evolving Treatment Strategies in DLBCL: Real-World Clinical Experience

EP. 4 DLBCL Subtype Response Patterns: Optimizing Treatment Selection

EP. 4 DLBCL Subtype Response Patterns: Optimizing Treatment Selection

EP. 5 Disease Progression in DLBCL: Management Strategies and Quality-of-Life Considerations

EP. 5 Disease Progression in DLBCL: Management Strategies and Quality-of-Life Considerations

EP. 6 Treatment Decision-Making in DLBCL: Balancing Efficacy, Safety, and Patient Factors

EP. 6 Treatment Decision-Making in DLBCL: Balancing Efficacy, Safety, and Patient Factors

EP. 7 Long-Term Data and Future Directions in First-Line DLBCL Treatment

EP. 7 Long-Term Data and Future Directions in First-Line DLBCL Treatment

Video content above is prompted by the following:

Please describe how disease progression impacts patients with DLBCL and the approaches to managing progressive disease based on first-line therapy selection.
• How do the POLARIX 5-year subsequent treatment data inform your approach, and what quality-of-life considerations influence your treatment approach?

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