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Opinion|Videos|March 31, 2025

Long-Term Outcomes and Treatment Guidelines in DLBCL Management

Author(s)Gilles Salles, MD, PhD, Matthew A. Lunning, DO, FACP

Experts discuss how the 5-year outcomes of polatuzumab have influenced its position in current NCCN guidelines for diffuse large B-cell lymphoma (DLBCL) treatment, offering insights on how to interpret and apply these recommendations in various patient scenarios.

Episodes in this series

EP. 1 Advances in DLBCL Management: Long-Term Treatment Outcomes

EP. 1 Advances in DLBCL Management: Long-Term Treatment Outcomes

EP. 2 Long-Term Outcomes and Treatment Guidelines in DLBCL Management

EP. 2 Long-Term Outcomes and Treatment Guidelines in DLBCL Management

EP. 3 Evolving Treatment Strategies in DLBCL: Real-World Clinical Experience

EP. 3 Evolving Treatment Strategies in DLBCL: Real-World Clinical Experience

EP. 4 DLBCL Subtype Response Patterns: Optimizing Treatment Selection

EP. 4 DLBCL Subtype Response Patterns: Optimizing Treatment Selection

EP. 5 Disease Progression in DLBCL: Management Strategies and Quality-of-Life Considerations

EP. 5 Disease Progression in DLBCL: Management Strategies and Quality-of-Life Considerations

EP. 6 Treatment Decision-Making in DLBCL: Balancing Efficacy, Safety, and Patient Factors

EP. 6 Treatment Decision-Making in DLBCL: Balancing Efficacy, Safety, and Patient Factors

EP. 7 Long-Term Data and Future Directions in First-Line DLBCL Treatment

EP. 7 Long-Term Data and Future Directions in First-Line DLBCL Treatment

Video content above is prompted by the following:

Please explain how the 5-year outcomes have impacted polatuzumab’s position in current NCCN guidelines for DLBCL treatment.
- How do you interpret and apply these guideline recommendations across patient scenarios?

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