NEWS
CONFERENCES
MEDIA
PUBLICATIONS
CASE-BASED ROUNDTABLE
PARTNERS
RESOURCES
SUBSCRIBE

Your AI-Trained Oncology Knowledge Connection!

Opinion|Videos|January 17, 2025

Diving Deep Into the CEPHEUS Trial: Subcutaneous Dara-VRd vs VRd in Transplant-Ineligible or Transplant-Deferred NDMM

Author(s)Rafael Fonseca, MD, Binod Dhakal, MD, MS, Doris K. Hansen, MD

Panelists discuss how the CEPHEUS trial demonstrates the comparative efficacy and safety of subcutaneous daratumumab combined with VRd vs VRd alone in patients with transplant-ineligible or transplant-deferred newly diagnosed multiple myeloma, highlighting key outcomes and clinical implications.

Episodes in this series

4 experts are featured in this series.

EP. 1 Expert Insights: Navigating the Evolving Treatment Landscape in NDMM

4 experts are featured in this series.

EP. 2 Clinical Insights: Starting with a Patient Case 1: 74yo 74-Year-Old Patient With NDMM Transplant- Ineligible NDMM

4 experts are featured in this series.

EP. 3 Evaluating Guideline-Recommended Treatment Options for Transplant-Ineligible or Transplant-Deferred NDMM

4 experts are featured in this series.

EP. 4 Diving Deep Into the CEPHEUS Trial: Subcutaneous Dara-VRd vs VRd in Transplant-Ineligible or Transplant-Deferred NDMM

4 experts are featured in this series.

EP. 5 IMROZ Data Highlights and Clinical Insights Into Quadruplet CD38-Containing Regimens in Transplant-Ineligible NDMM

4 experts are featured in this series.

EP. 6 Patient Case 2: A 65-Year-Old Patient With Standard-Risk, Transplant-Eligible NDMM

4 experts are featured in this series.

EP. 7 Selecting Among Guideline Recommended Treatment Options in Transplant-Eligible NDMM

4 experts are featured in this series.

EP. 8 PERSEUS Trial Highlights: Dara-VRd vs VRd in Transplant-Eligible NDMM

4 experts are featured in this series.

EP. 9 Clinical Perspectives: Question to Start Asking Is Who Not to Give Quadruplet CD38-Containing Regimens in Transplant-Eligible NDMM

4 experts are featured in this series.

EP. 10 Exploring Maintenance Strategies Post Autologous Transplant

4 experts are featured in this series.

EP. 11 Patient Case 4: A 58-Year-Old Woman With High-Risk MM Post HSCT With Progressive Disease—What Are Next Steps?

4 experts are featured in this series.

EP. 12 Patient Case 4: A 38-Year-Old Woman With Functional High-Risk MM With Progressive Disease at Day 60 Post ASCT—Next Treatment Approaches

4 experts are featured in this series.

EP. 13 Strategies to Overcome CAR T Roadblocks in the Real-World Practice Setting

4 experts are featured in this series.

EP. 14 CARTITUDE-4 Highlights: Cilta-Cel vs Standard of Care in R/R MM

4 experts are featured in this series.

EP. 15 CARTITUDE-4: Navigating Late CAR-T Toxicities

4 experts are featured in this series.

EP. 16 Patient Case 5: A 66-Year-Old Patient With R/R MM With Relapse Less Than 2 Years Post ASCT—Next Steps

4 experts are featured in this series.

EP. 17 KarMMa-3 Highlights: Ide-Cel vs Standard Regimens in Triple-Class– Exposed RRMM

4 experts are featured in this series.

EP. 18 KarMMa-3 Trial: Additional Insights From Ide-Cel in RRMM

4 experts are featured in this series.

EP. 19 Future Outlooks for CAR T in Early R/R Multiple Myeloma

Newsletter

Stay up to date on practice-changing data in community practice.

Related Content

1 expert is featured in this series.

Clinical Framing and Prognostic Assessment in Progressive Small Bowel Neuroendocrine Tumors

ByChristopher Lieu, MD, FASCO

February 1st 2026

FDA Grants FTD to GPRC5D Bispecific LBL-034 for R/R Multiple Myeloma

ByJonah Feldman

January 29th 2026

Comparing Teclistamab Trial Designs for Early Relapsed Multiple Myeloma

ByRoberto Mina, MD

January 29th 2026

FDA Approves Daratumumab Quadruplet for Transplant-Ineligible Myeloma

ByJonah Feldman

January 27th 2026

FDA Grants Fast Track Designation to IBI3003 for R/R Multiple Myeloma

ByJonah Feldman

January 27th 2026

Latest CME

Community Oncology Connections™: Beyond Primary End Points—Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Washington State Medical Oncology Society

Community Oncology Connections™: Beyond Primary End Points—Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Washington State Medical Oncology Society

Marla D. Lipsyc-Sharf, MD; Ashley Frith, MD

The Inaugural Hawaii Breast Cancer: A Multidisciplinary Case-Based Conference

The Inaugural Hawaii Breast Cancer: A Multidisciplinary Case-Based Conference

Hope S. Rugo, MD, FASCO; Naoto T. Ueno, MD, PhD

43rd Annual Miami Breast Cancer Conference®

In-Person Event

43rd Annual Miami Breast Cancer Conference®

March 5-8, 2026

Medical Crossfire®: Translating Evidence to Clinical Practice in Early-Stage HR+, HER2– Breast Cancer

Medical Crossfire®: Translating Evidence to Clinical Practice in Early-Stage HR+, HER2– Breast Cancer

Joyce O’Shaughnessy, MD; William J. Gradishar, MD, FASCO, FACP; Heather McArthur, MD, MPH

Updates and Innovations in Nonopioid Pain Management Strategies for Breast Cancer Patients Postsurgical Intervention

Updates and Innovations in Nonopioid Pain Management Strategies for Breast Cancer Patients Postsurgical Intervention

Patrick I. Borgen, MD; Joshua Feinberg, MD; Gary Schwartz, MD, FASA

Shaping Surgical Pathways: Revolutionizing Breast Cancer Care With Genetic Testing and Targeted Treatment

Shaping Surgical Pathways: Revolutionizing Breast Cancer Care With Genetic Testing and Targeted Treatment

Patrick I. Borgen, MD; E. Shelley Hwang, MD, MPH; Mark E. Robson, MD

Community Practice Connections™: Optimizing Treatment Outcomes and Preserving Fertility in Premenopausal HR+ Breast Cancer

Community Practice Connections™: Optimizing Treatment Outcomes and Preserving Fertility in Premenopausal HR+ Breast Cancer

Rebecca Shatsky, MD; Kelly McCann, MD, PhD; Michelle L. Taylor, ANP-BC

Community Practice Connections™: Navigating the Impact of HER2, HER3 and TROP2 from Early Stage to Advanced Breast Cancer Care

Community Practice Connections™: Navigating the Impact of HER2, HER3 and TROP2 from Early Stage to Advanced Breast Cancer Care

Hope S. Rugo, MD, FASCO; Sara Hurvitz, MD, FACP; Jennifer Litton, MD, MHCM; Heather McArthur, MD, MPH

Innovations in HR+/HER2– Metastatic Breast Cancer: Advancing Care Through PROTAC ER Degradation

Innovations in HR+/HER2– Metastatic Breast Cancer: Advancing Care Through PROTAC ER Degradation

Rita Nanda, MD; William Gradishar, MD, FASCO, FACP; Komal Jhaveri, MD, FACP; Kevin Kalinsky, MD, MS

Community Practice Connections™: Exploring Emerging Next-Generation Endocrine Therapies in ER+/HER2- Breast Cancer – Evaluating the Potential of Future of Treatment

Community Practice Connections™: Exploring Emerging Next-Generation Endocrine Therapies in ER+/HER2- Breast Cancer – Evaluating the Potential of Future of Treatment

Heather McArthur, MD, MPH; Komal Jhaveri, MD, FACP; Sara Tolaney, MD, MPH; Seth A. Wander, MD, PhD

Community Practice Connections™: Translating Evidence to Clinical Practice in Early-Stage HR+, HER2- Breast Cancer

Community Practice Connections™: Translating Evidence to Clinical Practice in Early-Stage HR+, HER2- Breast Cancer

Joyce O’Shaughnessy, MD; William Gradishar, MD, FASCO, FACP; Heather McArthur, MD, MPH; Eleni Anastasia Tousimis, MD, MBA, FACS

Clinical Case Vignette Series™: 42nd Annual Miami Breast Cancer Conference®

Clinical Case Vignette Series™: 42nd Annual Miami Breast Cancer Conference®

Reshma Jagsi, MD, DPhil; Kevin Kalinsky, MD, MS; Hope S. Rugo, MD, FASCO; Alastair Thompson, MD, MBChB, BSc (Hons), FRCS (Ed), FACS

Breast Cancer Tumor Board®: Advancing Care in Metastatic Breast Cancer - The Evolving Role of Antibody-Drug Conjugates

Breast Cancer Tumor Board®: Advancing Care in Metastatic Breast Cancer - The Evolving Role of Antibody-Drug Conjugates

Aditya Bardia, MD, MPH, FASCO; Joyce O’Shaughnessy, MD; Hope S. Rugo, MD; Paolo Tarantino, MD

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

William J. Gradishar, MD, FASCO, FACP; Laura Huppert, MD; Yuan Yuan, MD, PhD

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Joyce O’Shaughnessy, MD; Matthew P. Goetz, MD; Hope S. Rugo, MD, FASCO

Trending on Targeted Oncology - Immunotherapy, Biomarkers, and Cancer Pathways

FDA Accepts BLA for Ivonescimab in Pretreated EGFR-Mutated NSCLC

The Targeted Pulse: New Standards in Myeloma, Melanoma, and More

Onvansertib Triplet Shows Dose-Dependent Frontline Benefit in RAS-Mutant Metastatic CRC

Pembrolizumab/Lenvatinib Show Efficacy, Safety in Clear Cell Gyn Cancers

NCCN Updates Breast Cancer Guidelines: Sacituzumab Govitecan for 1L TNBC