Opinion|Videos|July 1, 2026

Durability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

Author(s)Misako Nagasaka, MD, PhD

Misako Nagasaka, MD, PhD, discusses the overall response rate and duration of response with subcutaneous (SC) amivantamab plus lazertinib in patients with treatment-naïve, EGFR-mutated advanced non–small cell lung cancer, as reported from the PALOMA-2 trial. She explains the significance of the durability demonstrated by the SC regimen in the frontline setting for EGFR-mutated advanced NSCLC.

Episodes in this series

1 expert is featured in this series

EP. 1 Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 2 PFS Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 3 Durability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 4 Tolerability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 5 Optimal Patient Management With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 6 Prophylactic Anticoagulation With Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 7 Practical Considerations With Frontline SC Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 8 SC Amivantamab Plus Lazertinib Builds on Evolving Frontline Paradigm in EGFR+ NSCLC

Dr. Nagasaka declares that her personal opinions/thoughts are hers and not those of UCI Health, UC Regents, and any other related entities.

Misako Nagasaka, MD, PhD, discusses the overall response rate and duration of response with subcutaneous (SC) amivantamab plus lazertinib in patients with treatment-naïve, EGFR-mutated advanced non–small cell lung cancer, as reported from the PALOMA-2 trial. She explains the significance of the durability demonstrated by the SC regimen in the frontline setting for EGFR-mutated advanced NSCLC.

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