Opinion|Videos|July 1, 2026

Practical Considerations With Frontline SC Amivantamab Plus Lazertinib in EGFR+ NSCLC

Author(s)Misako Nagasaka, MD, PhD

Misako Nagasaka, MD, PhD, discusses practical considerations for oncologists implementing subcutaneous (SC) vs intravenous (IV) amivantamab plus lazertinib in the frontline setting for patients with EGFR-mutated advanced or metastatic non–small cell lung cancer. Nagasaka recommends the SC over the IV regimen in the frontline setting, particularly when focusing on convenience and patients’ quality of life.

Episodes in this series

1 expert is featured in this series

EP. 1 Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 2 PFS Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 3 Durability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 4 Tolerability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 5 Optimal Patient Management With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 6 Prophylactic Anticoagulation With Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 7 Practical Considerations With Frontline SC Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 8 SC Amivantamab Plus Lazertinib Builds on Evolving Frontline Paradigm in EGFR+ NSCLC

Dr. Nagasaka declares that her personal opinions/thoughts are hers and not those of UCI Health, UC Regents, and any other related entities.

Misako Nagasaka, MD, PhD, discusses practical considerations for oncologists implementing subcutaneous (SC) vs intravenous (IV) amivantamab plus lazertinib in the frontline setting for patients with EGFR-mutated advanced or metastatic non–small cell lung cancer. Nagasaka recommends the SC over the IV regimen in the frontline setting, particularly when focusing on convenience and patients’ quality of life.

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