Opinion|Videos|July 1, 2026

SC Amivantamab Plus Lazertinib Builds on Evolving Frontline Paradigm in EGFR+ NSCLC

Author(s)Misako Nagasaka, MD, PhD

Misako Nagasaka, MD, PhD, describes how it is a “great time to be a thoracic oncologist” with the constantly expanding armamentarium in the field. She specifically discusses the available treatment options in frontline EGFR mutation–positive advanced non–small cell lung cancer and what particular clinical and lifestyle benefits are provided by the treatment regimen of subcutaneous amivantamab plus lazertinib.

Episodes in this series

1 expert is featured in this series

EP. 1 Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 2 PFS Outcomes With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 3 Durability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 4 Tolerability of SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 5 Optimal Patient Management With SC Amivantamab Plus Lazertinib in Frontline EGFR+ NSCLC

1 expert is featured in this series

EP. 6 Prophylactic Anticoagulation With Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 7 Practical Considerations With Frontline SC Amivantamab Plus Lazertinib in EGFR+ NSCLC

1 expert is featured in this series

EP. 8 SC Amivantamab Plus Lazertinib Builds on Evolving Frontline Paradigm in EGFR+ NSCLC

Dr. Nagasaka declares that her personal opinions/thoughts are hers and not those of UCI Health, UC Regents, and any other related entities.

Misako Nagasaka, MD, PhD, describes how it is a “great time to be a thoracic oncologist” with the constantly expanding armamentarium in the field. She specifically discusses the available treatment options in frontline EGFR mutation–positive advanced non–small cell lung cancer and what particular clinical and lifestyle benefits are provided by the treatment regimen of subcutaneous amivantamab plus lazertinib.

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