Impact of Pertuzumab in HER2-Positive Breast Cancer

December 8, 2018
Charles E. Geyer, Jr, MD

Charles E. Geyer, Jr, MD, professor of medicine at Virginia Commonwealth University School of Medicine, associate director for clinical research and Harrigan, Haw, Luck Families Chair in Cancer Research at Massey Cancer Center, discusses the impact of pertuzumab (Perjeta) in the treatment of patients with HER2-positive breast cancer at the 2018 San Antonio Breast Cancer Symposium.

Charles E. Geyer, Jr, MD, professor of medicine at Virginia Commonwealth University School of Medicine, associate director for clinical research and Harrigan, Haw, Luck Families Chair in Cancer Research at Massey Cancer Center, discusses the impact of pertuzumab (Perjeta) in the treatment of patients with HER2-positive breast cancer at the 2018 San Antonio Breast Cancer Symposium.

Pertuzumab is a very important drug in the early treatment of patients with HER2-positive breast cancer, explains Geyer. In large part, its efficacy was demonstrated in results of the CLEOPATRA trial in metastatic disease. These antibodies were developed with an intent to engage the immune system, and they had yet to demonstrate that intent until CLEOPATRA, says Geyer.