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Opinion|Videos|February 27, 2025

Initial Treatment Options for Liver-Confined Unresectable HCC

Author(s)Amit Singal, MD

The panelist discusses first-line options including atezolizumab plus bevacizumab, lenvatinib, and sorafenib. Second-line treatments include regorafenib, cabozantinib, and ramucirumab. Clinical trials should be prioritized when available.

Episodes in this series

1 expert in this video

EP. 1 Unresectable HCC with Post-TACE Progression

1 expert in this video

EP. 2 Initial Treatment Options for Liver-Confined Unresectable HCC

1 expert in this video

EP. 3 Managing Disease Progression After TACE

1 expert in this video

EP. 4 Role of Systemic Therapy in TACE-Eligible Patients

1 expert in this video

EP. 5 Clinical Pearls in Intermediate Stage uHCC Management

Video content above is prompted by the following:

Please briefly review the treatment options for patients with hepatocellular carcinoma (HCC) confined to the liver but unresectable according to NCCN guidelines.
Please discuss standard treatment modalities and share your impressions on the initial treatment approach in this case.

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