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Opinion|Videos|March 4, 2025

Third-Line Treatments and Current Practice Guidelines in Advanced RCC

Author(s)Pedro Barata, MD, MSc, FACP

A panelist discusses how, based on the NCCN guidelines for kidney cancer, third-line treatment options for this patient include cabozantinib, lenvatinib plus everolimus, tivozanib, and everolimus monotherapy. Clinical trials and best supportive care remain important considerations at this stage.

Episodes in this series

1 expert in this video

EP. 1 Case 2: Patient With Relapsed/Recurrent Metastatic RCC

1 expert in this video

EP. 2 Treatment Goals for Transitioning From 2L to 3L mRCC

1 expert in this video

EP. 3 Third-Line Treatments and Current Practice Guidelines in Advanced RCC

1 expert in this video

EP. 4 A Review of Current and Emerging Clinical Data for 3L mRCC

1 expert in this video

EP. 5 Individualized Approaches in 3L Treatment Selection for mRCC

1 expert in this video

EP. 6 Sequencing Multiple Lines of Therapy in Metastatic RCC

1 expert in this video

EP. 7 Navigating TKI Toxicities: Expert Perspectives and Clinical Distinctions

Video content above is prompted by the following:

What are the third-line options for this patient per the NCCN guidelines for kidney cancer?

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