In the phase 3 EXCALIBER-RRMM trial, iberdomide plus daratumumab and dexamethasone doubled MRD-negative complete response rates over standard therapy in relapsed myeloma.
News|Articles|March 7, 2015
Thyroid Hormone Receptor and Runx2 Expression in Thyroid Cancer Cells
Author(s)Frances Carr, PhD
Frances Carr, PhD, professor, Department of Pharmacology, The University of Vermont, discusses the relationship between the thyroid hormone receptor and Runx2 expression in thyroid cancer cells.
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Frances Carr, PhD, professor, Department of Pharmacology, The University of Vermont, discusses the relationship between the thyroid hormone receptor and Runx2 expression in thyroid cancer cells.
- The thyroid hormone receptor is a possible tumor suppressor.
- Studies have shown that Runx2 may be a tumor promoter in papillary thyroid cancer.
- An inverse relationship was seen between thyroid hormone receptor expression and Runx2.
- This relationship is being explored and could have therapeutic implications in the future.
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