Translating Clinical Data Into Practice: Patient Considerations for Success with Prophylactic Management of Dermatologic AEs

EP: 1.1L Treatment for Advanced NSCLC

EP: 2.Insights from COCOON: Prophylactic Dermatologic Management With Amivantamab + Lazertinib in Advanced NSCLC

EP: 3.Clinical Approaches for Dermatologic AEs Associated With Amivantamab + Lazertinib in Advanced NSCLC

EP: 4.Clinical Impact of COCOON: Advancing Dermatologic AE Management

EP: 5.Translating Clinical Data Into Practice: Strategies to Implement Enhanced Dermatologic Management With Amivantamab + Lazertinib in Advanced NSCLC

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EP: 6.Translating Clinical Data Into Practice: Patient Considerations for Success with Prophylactic Management of Dermatologic AEs

EP: 7.Future Perspectives in 1L Treatment of Advanced NSCLC

Summary for Physicians: Strategies for Improving Patient Adherence to Prophylactic DAE Care

Effective Strategies for Patient Adherence:

1. Clear patient education:

• Providing thorough education on the importance of prophylactic care and the potential impact of DAEs on overall treatment success and quality of life.
• Explaining the direct relationship between prevention and the reduction of severe skin reactions, thus improving patient adherence.

2. Simplified skin care regimen:

• Creating an easy-to-follow skin care routine, ensuring that treatments such as moisturizers, sunscreens, and topical agents are practical and accessible for daily use.
• Using patient-friendly language to describe the products and their correct application to minimize confusion or overwhelm.

3. Personalized recommendations:

• Tailoring prophylactic strategies to the individual patient's skin type, cancer treatment plan, and lifestyle to increase relevance and adherence.
• Offering alternatives (eg, fragrance-free products or specific sunblocks) based on patient preferences or sensitivities.

4. Regular follow-up and monitoring:

• Establishing regular check-ins, either through in-person visits, telehealth, or through nurse-directed follow-up, to monitor the patient's adherence with the prescribed regimen.
• Reinforcing positive behaviors and addressing any barriers to adherence during these follow-up appointments.

5. Incorporating family or caregiver support:

• Engaging family members or caregivers in the patient’s skin care routine to help reinforce daily practices and ensure the patient stays on track with the regimen.
• Educating caregivers on the importance of dermatologic care as part of the overall treatment plan.

6. Incentivizing adherence:

• Using a reward system or positive reinforcement to celebrate adherence milestones, such as consistently following the skin care routine or attending follow-up appointments.

7. Addressing barriers to adherence:

• Identifying and addressing common barriers, such as cost of products, lack of time, or confusion about the treatment schedule.
• Offering low-cost or accessible alternatives and making sure patients understand how to integrate the care regimen into their daily lives.

Summary: By providing clear education, simplifying regimens, offering personalized recommendations, and fostering regular follow-ups, you can significantly enhance patient adherence to prophylactic dermatologic care. Engaging the patient’s support system and addressing potential barriers upfront can also play an important role in ensuring sustained adherence and, ultimately, better management of DAEs.