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Opinion|Videos|January 26, 2026

Future Directions in cGVHD Treatment

Leyla O. Shune, MD, looks to the future of treatment for patients with chronic graft-versus-host disease (cGVHD).

Leyla O. Shune, MD, looks to the future of treatment for patients with chronic graft-versus-host disease (cGVHD). She is hopeful for the potential of more effective, less toxic, steroid-sparing approaches that can emerge with novel agents being moved up earlier in the treatment paradigm. She is also excited for improved outcomes in patients with difficult-to-treat fibrotic cGVHD with the emergence of agents such as axatilimab.

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