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Opinion|Videos|January 12, 2026

Exploring Combination Therapy in Newly Diagnosed cGVHD

Leyla O. Shune, MD, discusses results from an interim safety analysis of a randomized phase 2 study exploring axatilimab in combination with ruxolitinib in patients with newly diagnosed chronic graft-versus-host disease.

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Leyla O. Shune, MD, discusses results from an interim safety analysis of a randomized phase 2 study exploring axatilimab in combination with ruxolitinib in patients with newly diagnosed chronic graft-versus-host disease. She explains how the results, which were presented at the 2025 ASH Annual Meeting, showed that no new safety signals emerged when combining the 2 agents compared with previously reported outcomes for single-agent use of the treatments.

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