Sabrina Serani is a senior editor for Targeted Oncology.
Investigational Assay Shows Promise as Prognostic Tool for Prostate Cancer
Investigators presented results from new studies at the 2023 ASTRO Meeting. The data showcase a new assay’s performance in predicting metastasis-free survival and distant metastasis.
Phase 3 Trial for Venetoclax for Multiple Myeloma Misses Its Primary End Point
The improvement in progression-free survival in the venetoclax arm of the study was not statistically significant compared to the control arm but results still trend positively.
Pembrolizumab Improves DFS in Muscle-Invasive Urothelial Carcinoma
Meeting a primary end point, KEYNOTE-123 study shows promise for pembrolizumab as an adjuvant muscle-invasive bladder cancer treatment.
FDA’S ODAC Votes Yes to Eflornithine for Pediatric Neuroblastomas
The decision marks the first time the FDA has relied on a single externally controlled trial to support a potential approval in oncology.
SAR-Bombesin Treatment in Prostate Cancer Begins
The phase 1/2 trial is evaluating 64Cu/67Cu SAR-Bombesin for diagnosis and treatment of castrate resistant prostate cancer.
FDA Grants Orphan Drug Designation to BDC-1001 in Gastric Cancer
Phase 2 studies are investigating BDC-1001 in HER2-positive gastroesophageal, colorectal, breast, and endometrial cancers.
Motixafortide Shows Benefit to First-Line Pancreatic Cancer Treatment in Phase 2 Trial
An MCGN drug combination shows potential to be more effective than standard chemotherapy alone for treatment-naïve metastatic pancreatic cancer.
Mirvetuximab Soravtansine Prolongs Survival in Ovarian Cancer Subset
Results of the phase 3 MIRASOL study evaluating mirvetuximab soravtansine for platinum-resistant ovarian cancer will be announced at an upcoming meeting.
GC012F CAR T Shows 100% Complete Response Rate in Multiple Myeloma
Researchers presented updated results from longer-term follow-up studies of GC012F for newly-diagnosed multiple myeloma treatment at the International Myeloma Society Annual Meeting.