April 27th 2024
Targeted therapies and immunotherapies across the ovarian, endometrial, and cervical cancers landscape play expanded roles, according to Ritu Salani, MD, MBA.
Community Practice Connections™: Real-World Applications of Novel Therapies Across TNBC and Addressing Disparities in Care
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Advances in TNBC: Communicating with Your Patients About Clinical Trial Awareness and Treatment Concerns to Improve Clinical Outcomes
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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Dr. Yael Cohen on VB111 as a Potential Treatment for Ovarian Cancer
December 28th 2015Yael Cohen, MD, discusses VB111, a highly targeted anti-angiogenic agent. The treatment is currently going through a phase III trial for treating glioblastoma, phase I trial for thyroid cancer and phase II trial for ovarian cancer.
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Link Discovered in Ovarian Cancer Between Adjuvant Hormonal Therapy and Improved Outcomes
December 23rd 2015A correlation was drawn between adjuvant hormone therapy (AHT) and a 37% reduction in the risk of death in women with epithelial ovarian cancer, according to results of a 24-year study.
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New Multimodal Ovarian Cancer Screening Tactic Shows Promise
December 23rd 2015A new method of screening utilizing CA-125 and a risk assessment algorithm could drop risk of mortality from ovarian cancer in certain women, according to findings from the UK Collaborative Trial of Ovarian Cancer Screening.
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Denosumab Shows Survival Boost in Postmenopausal Women
December 11th 2015A follow-up benefits analysis of adding denosumab to aromatase inhibitor (AI) therapy shows the agent not only helps prevent fractures, it also reduces risk of recurrence and death in postmenopausal women with HR-positive breast cancer.
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Roll-Your-Own-Tumor Technology for Cancer Research May Boost Personalized Treatments
December 1st 2015Details of a new technology for studying tumor metabolism have been published in Nature Materials, whereby a cellulose strip containing tumor cells was wrapped around a metal core and incubated, mimicking conditions consistent with in vivo tumors.
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Dr. Thomas Herzog on the Cautions of Interval Debulking Surgery in Ovarian Cancer
November 25th 2015Thomas Herzog, MD, on the cautions of interval debulking surgery in ovarian cancer and its difference from neoadjuvant treatment. Herzog said interval debulking surgery entails an initial, maximum surgical effort that is followed up by chemotherapy.
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Dr. Jeffrey Infante on the Positive Results of Using Avelumab in Patients With Ovarian Cancer
November 10th 2015Jeffrey R. Infante, MD director of Drug Development, Sarah Cannon Research Institute, talks about the anti-PD-L1 antibody avelumab in patients with previously treated, recurrent or refractory ovarian cancer.
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Dr. Maurie Markman on the Further Study of PD-1 Inhibitors in Ovarian Cancer
November 5th 2015Maurie Markman, MD, president of Medicine and Science, Eastern Regional Medical Center, talks about use of PD-1 inhibitors in ovarian cancer and the lack of evidence pointing toward their functionality.
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Acute lymphoblastic leukemia (ALL) is a relatively rare malignancy in adults, with an estimated 6250 new cases and 1450 deaths expected in the United States in 2015. Although most patients achieve complete remission with conventional combination chemotherapy regimens, at least two-thirds of high-risk patients relapse.2 While overall survival for children has significantly improved in the last 30 years, newly diagnosed adults continue to have a poor 5-year OS rate, approximating 35%, depending on age and risk factors.
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Trend Toward Less Bowel Toxicity for IMRT Versus 3-D Conformal RT in Cervical Cancer
October 23rd 2015Intensity-modulated radiation therapy (IMRT) for cervical cancer has led to a double-digit decrease in late bowel toxicity compared with 3-D conformal radiation therapy without statistical significance.
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Key to New Treatments: Discovering What Turns a Hedgehog Off
October 14th 2015Researchers note that chronic Hedgehog (Hh) pathway stimulation has been shown in prostate, lung, and ovarian cancers, and that zinc levels decrease early in prostate cancer continuing to castration-resistant disease. Researchers are exploring whether or not zinc may suppress the autocatalysis in the Hh precursor and inhibit production of biologically active Hh ligand.
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Dr. Kauff Discusses Remaining Questions in the Treatment of Patients With Uterine Cancer
October 8th 2015Noah D. Kauff, MD, FACOG, gynecologist and geneticist, director, Ovarian Cancer Screening and Prevention, Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, discusses unanswered questions regarding the treatment of patients with uterine cancer.
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HCC Survival Impacted by Radiofrequency Ablation Dwell Time
October 5th 2015A more than 25-month improvement in overall survival was seen with lyso-thermosensitive liposomal doxorubicin (LTLD; ThermoDox) combined with optimized (?45 minutes dwell time) radiofrequency ablation in patients with hepatocellular carcinoma.
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Dr. Frederic Amant on the Safety of Chemotherapy During Pregnancy
October 1st 2015Frederic Amant, MD, PhD, assistant professor, gynecologic oncologist, head of the scientific section of gynecologic oncology at Katholieke Universiteit in Leuven, Belgium, the impacts of chemotherapy on pregnant woman and their babies.
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Novel Immunotherapy for Metastatic Cervical Cancer Shows Survival Benefit
October 1st 2015Tom Herzog, MD, clinical director, University of Cincinnati Cancer Institute, explains the impact ADXS11-001 may have on patients with recurrent metastatic cervical cancer who currently have limited effective treatment options.
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Women Receiving Chemoradiotherapy for Cervical Cancer Achieve Emesis Control With Fosaprepitant
October 1st 2015Significantly improved emesis control was seen when fosaprepitant was added to an antiemetic regimen compared with standard care, in women receiving radiotherapy and cisplatin for cervical cancer.
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