May 20th 2025
In an 8 to 1 vote, the Oncologic Drug Advisory Committee determined that findings from the phase 3 STARGLO trial are not applicable to patients in the US with diffuse large B-cell lymphoma.
January 17th 2025
December 10th 2024
How Will New Immunotherapies Fit Into the Treatment Landscape of Follicular Lymphoma?
October 4th 2022Future directions for follicular lymphoma treatments include potential use earlier in treatment or as combination therapy, identifying patients who will benefit most from treatment, and minimizing the costs of therapy while maximizing accessibility.
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CD20/CD3 Bispecific Antibodies Can Revolutionize B-Cell Lymphoma Therapy
October 3rd 2022The bispecific antibodies for B-cell lymphoma that are under development target CD20, and they have a second receptor that targets CD3, which is present on vector T cells, according to Loretta J. Nastoupil, MD.
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Immune Checkpoint Inhibitors and Novel Agents Are Explored in Hodgkin Lymphoma
September 30th 2022As the brentuximab vedotin plus AVD combination gains widespread use, clinicians should recognize the toxicities, such as the risk of neutropenic fever or peripheral neuropathy, according to Alison Moskowitz, MD.
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VITALIZE Trial Explores Maveropepimut-S/Pembrolizumab in Relapsed/Refractory DLBCL
September 15th 2022In an interview with Targeted Oncology, Matthew Matasar, MD, discusses background information on the ongoing VITALIZE trial of maveropepimut-S in patients with diffuse large B-cell lymphoma.
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FDA Lifts Partial Clinical Hold on TakeAim Lymphoma Study of Emavusertib/Ibrutinib
August 19th 2022The TakeAim Lymphoma study will continue to evaluate emavusertib with or without ibrutinib in patients with various types of lymphoma after a 4 1/2-month partial clinical hold placed by the FDA.
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FDA Accepts sBLA for Polatuzumab Vedotin Combination in Previously Untreated DLBCL
August 16th 2022By April 2023, the FDA plans have a decision on the approval application for polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisone as an option for treatment-naïve diffuse large B-cell lymphoma.
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