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Opinion|Videos|January 9, 2025

Case 1 Presentation (cont): mHSPC

Author(s)Evan Y. Yu, MD

Evan Y. Yu, MD, discusses how the presentation of a patient with metastatic hormone-sensitive prostate cancer (mHSPC) involves evaluating key clinical features such as disease extent, symptoms, and performance status to guide treatment decisions and the selection of appropriate systemic therapies.

Episodes in this series

EP. 1 Introduction & Case 1 Presentation: mHSPC

EP. 1 Introduction & Case 1 Presentation: mHSPC

EP. 2 Newly diagnosed Diagnosed mHSPC: Goals of Therapy

EP. 2 Newly diagnosed Diagnosed mHSPC: Goals of Therapy

EP. 3 Newly Diagnosed mHSPC: First-Line Treatment Options

EP. 3 Newly Diagnosed mHSPC: First-Line Treatment Options

EP. 4 Newly Diagnosed mHSPC: Androgen Receptor Pathway Inhibitor Selection

EP. 4 Newly Diagnosed mHSPC: Androgen Receptor Pathway Inhibitor Selection

EP. 5 Case 1 Presentation (cont): mHSPC

EP. 5 Case 1 Presentation (cont): mHSPC

EP. 6 Phase 3 ARANOTE Study of ADT + Darolutamide

EP. 6 Phase 3 ARANOTE Study of ADT + Darolutamide

EP. 7 Phase 3 ARANOTE Study of ADT + Darolutamide: Safety

EP. 7 Phase 3 ARANOTE Study of ADT + Darolutamide: Safety

EP. 8 mHSPC: Applying Data Toward Treatment Decision-Making

EP. 8 mHSPC: Applying Data Toward Treatment Decision-Making

EP. 9 Adding Chemotherapy for a Patient Receiving ADT + an ARPI

EP. 9 Adding Chemotherapy for a Patient Receiving ADT + an ARPI

EP. 10 Case 2 Presentation: mCRPC

EP. 10 Case 2 Presentation: mCRPC

Video content above is prompted by the following:

Please discuss how you approach individualized first-line systemic therapy selection for patients with metastatic hormone-sensitive prostate cancer (mHSPC).
1. Please offer perspectives on pros/cons of current options for first-line therapy.
2. What factors do you consider during treatment decision-making (eg, use of chemotherapy-sparing regimens, ARPI selection, triplet versus doublet combination systemic therapy)?

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