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Opinion|Videos|March 31, 2025

Clinical Case – A Patient With Steroid-Refractory cGVHD

Author(s)Nelson Chao, MD, MBA

A panelist discusses how graft-vs-host disease (GVHD) manifests through a complex constellation of symptoms affecting multiple organ systems, including the skin (rash, itching), gastrointestinal tract (diarrhea, nausea, abdominal pain), liver (elevated enzymes, jaundice), and lungs (shortness of breath, cough), with severity assessment typically following established criteria.

Episodes in this series

1 expert is featured in this series.

EP. 1 Clinical Case – A Patient With Steroid-Refractory cGVHD

1 expert is featured in this series.

EP. 2 Current Practices and Initial Treatment Considerations for Patients With cGVHD

1 expert is featured in this series.

EP. 3 Long-Term Outcomes of Ruxolitinib Therapy in Patients With cGVHD

1 expert is featured in this series.

EP. 4 Ruxolitinib Therapy for cGVHD: Insights on Patient and Safety Monitoring

1 expert is featured in this series.

EP. 5 The Treatment Landscape for cGVHD: From Current Practices to Evolving Therapies

1 expert is featured in this series.

EP. 6 Academic Perspectives and Key Considerations for Optimal Patient Care in cGVHD

Video content above is prompted by the following:

Please give a high-level overview of GVHD symptoms/presentation and how GVHD is assessed.
What is your initial approach to therapy, and what immediate or long-term factors do you consider when making your initial treatment decisions?

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