Clinical Case – A Patient With Steroid-Refractory cGVHD

Opinion
Video

A panelist discusses how graft-vs-host disease (GVHD) manifests through a complex constellation of symptoms affecting multiple organ systems, including the skin (rash, itching), gastrointestinal tract (diarrhea, nausea, abdominal pain), liver (elevated enzymes, jaundice), and lungs (shortness of breath, cough), with severity assessment typically following established criteria.

Video content above is prompted by the following:

  • Please give a high-level overview of GVHD symptoms/presentation and how GVHD is assessed.
  • What is your initial approach to therapy, and what immediate or long-term factors do you consider when making your initial treatment decisions?

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