
Opinion|Videos|April 28, 2025
The Treatment Landscape for cGVHD: From Current Practices to Evolving Therapies
Author(s)Nelson Chao, MD, MBA
A panelist discusses how the treatment landscape for chronic graft-vs-host disease (cGVHD) has evolved significantly in recent years, with several pivotal clinical trials beyond REACH3 informing our approach, including the REACH1 and REACH2 trials for acute GVHD; the ROCKstar trial supporting belumosudil approval; and studies evaluating ibrutinib, axatilimab, and extracorporeal photopheresis.
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Episodes in this series

Video content above is prompted by the following:
- Please review the treatment landscape; how do other trials inform treatment?
- What other treatment strategies are available?
- Which patients do you think are best suited to receive ruxolitinib therapy?
- Where do you think the future of cGVHD treatment is heading?
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