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Opinion|Videos|April 28, 2025

The Treatment Landscape for cGVHD: From Current Practices to Evolving Therapies

A panelist discusses how the treatment landscape for chronic graft-vs-host disease (cGVHD) has evolved significantly in recent years, with several pivotal clinical trials beyond REACH3 informing our approach, including the REACH1 and REACH2 trials for acute GVHD; the ROCKstar trial supporting belumosudil approval; and studies evaluating ibrutinib, axatilimab, and extracorporeal photopheresis.

Episodes in this series

Video content above is prompted by the following:

  • Please review the treatment landscape; how do other trials inform treatment?
  • What other treatment strategies are available?
  • Which patients do you think are best suited to receive ruxolitinib therapy?
  • Where do you think the future of cGVHD treatment is heading?

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