Opinion|Videos|April 14, 2025
Long-Term Outcomes of Ruxolitinib Therapy in Patients With cGVHD
Author(s)Nelson Chao, MD, MBA
A panelist discusses how identifying steroid-dependent or steroid-refractory (SR) graft-vs-host disease (GVHD) requires careful clinical monitoring, with the determination typically made when patients show disease progression during prednisone taper, inadequate response after 5 to 7 days of treatment, or persistent disease despite 2 weeks of appropriate steroid therapy.
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Episodes in this series
Video content above is prompted by the following:
- Moving into steroid-dependent or SR cases, how do you determine a treatment approach?
- Please discuss efficacy and safety from REACH3 3-year final analysis.
- What are clinical implications from the failure-free survival and duration of response data?
- How has your clinical practice adapted given these data?
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