Adverse Events Monitoring and Management in BPDCN Treatment

Opinion
Video

An expert discusses how monitoring capillary leakage syndrome (CLS) requires vigilant assessment of fluid balance, hemodynamics, and biomarkers. Academic settings may have advanced resources, whereas community settings rely on standardized protocols. Key adverse effects include hypotension, edema, and organ dysfunction. Management includes fluid resuscitation, vasopressors, and close monitoring.

Video content above is prompted by the following:

  • What protocols/strategies do you implement to monitor CLS?
  • What are specific considerations (ie, academic vs community setting)?
  • What other adverse effects are critical to monitor?
  • What strategies can be implemented to mitigate/manage them?

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