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Opinion|Videos|April 1, 2025

Treatment Implementation and Long-Term Considerations in BPDCN

Author(s)Marlise R. Luskin, MD, MSCE

Panelists discuss how optimizing shared-care models between academic and community centers enhances continuity in complex hematologic malignancies. Key monitoring parameters for tagraxofusp include capillary leak syndrome risk. Timely transplant referral depends on disease kinetics. Novel therapies are among the unmet needs in plasmacytoid dendritic cell neoplasm. Support resources aid patient management. Emerging treatments and clinical insights continue to advance care.

Episodes in this series

1 expert in this video

EP. 1 A 62-Year-Old Man Who Is Newly Diagnosed With BPDCN

1 expert in this video

EP. 2 Understanding BPDCN: From Disease Presentation to Diagnosis

1 expert in this video

EP. 3 An Overview of Treatment Approaches for BPDCN

1 expert in this video

EP. 4 The Role of CD123 Targeted Therapy (tagraxofusp) in the Evolving Treatment Landscape for BPDCN

1 expert in this video

EP. 5 Academic Perspectives on Treatment Decisions for BPDCN

1 expert in this video

EP. 6 Adverse Events Monitoring and Management in BPDCN Treatment

1 expert in this video

EP. 7 Treatment Implementation and Long-Term Considerations in BPDCN

Video content above is prompted by the following:

What are effective strategies to structure the shared-care model between academic and community centers?
What specific parameters are critical to monitor when using tagraxofusp in the community setting?
What factors influence the timing of transplant referral in patients who achieve complete response with initial therapy?
What unmet needs remain in managing blastic plasmacytoid dendritic cell neoplasm(BPDCN)?
What are resources/support systems for patients with complex hematologic malignancies?
What clinical pearls and up-and-coming treatment strategies are you excited about?

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