Opinion|Videos|March 18, 2025
The Role of CD123 Targeted Therapy (tagraxofusp) in the Evolving Treatment Landscape for BPDCN
Author(s)Marlise R. Luskin, MD, MSCE
An expert discusses how medical professionals have integrated tagraxofusp into blastic plasmacytoid dendritic cell neoplasm (BPDCN) treatment, leveraging its CD123-targeted efficacy per 0114 trial data. Real-world findings (Angelucci et al, ASH 2023) align with clinical outcomes, reinforcing tagraxofusp’s role in BPDCN management by supporting its safety and effectiveness in broader settings.
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Episodes in this series
Video content above is prompted by the following:
- Given the efficacy/safety data from the 0114-trial evaluating tagraxofusp in BPDCN, how have you adapted your treatment approach to incorporate CD123 targeted therapy?
- Do real-world data (Angelucci et al, ASH 2023) of tagraxofusp in BPDCN complement trial data?
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