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Opinion|Videos|January 8, 2025

Novel Updates in Second-line Therapies for LR-MDS

Panelists discuss real-world evidence on dose escalation of luspatercept in lower-risk myelodysplastic syndrome (LR-MDS) (Patel et al, EHA 2024), highlighting its clinical benefits in improving patient outcomes, and share insights from the MAXILUS trial (Della Porta et al, EHA 2024), considering how this dosing strategy could influence clinical practice and enhance patient care.

Episodes in this series
  1. Please briefly discuss real-world evidence of dose escalation of luspatercept in LR-MDS (Patel et al, EHA 2024).
    1. What are the clinical benefits and how can dose escalation in practice improve patient outcomes?
  2. Please briefly discuss the MAXILUS trial (Della Porta et al, EHA 2024).
    1. What are your thoughts on this dosing strategy?
    2. How could this strategy influence care in the clinic?

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