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Opinion|Videos|March 6, 2025

PEACE-3 Study Results: Efficacy

Author(s)Abhishek Tripathi, MD

An expert discusses the key efficacy findings from the PEACE-3 study, including results on radiographic progression-free survival (rPFS) and overall survival (OS), and offers insights on how to interpret and apply these results in clinical practice.

Episodes in this series

EP. 1 Case presentation: Patient with metastatic CRPC after ARPI and docetaxel for localized PC

EP. 1 Case presentation: Patient with metastatic CRPC after ARPI and docetaxel for localized PC

EP. 2 Therapeutic options for a patient with mCRPC after ADT + docetaxel

EP. 2 Therapeutic options for a patient with mCRPC after ADT + docetaxel

EP. 3 PEACE-3 study of enzalutamide + Ra-223 for ARPI-naïve mCRPC: Design and objectives

EP. 3 PEACE-3 study of enzalutamide + Ra-223 for ARPI-naïve mCRPC: Design and objectives

EP. 4 PEACE-3 Study Results: Study Population & Disposition

EP. 4 PEACE-3 Study Results: Study Population & Disposition

EP. 5 PEACE-3 Study Results: Efficacy

EP. 5 PEACE-3 Study Results: Efficacy

EP. 6 PEACE-3 Study Results: Safety

EP. 6 PEACE-3 Study Results: Safety

EP. 7 How would therapeutic options change if this patient was asymptomatic?

EP. 7 How would therapeutic options change if this patient was asymptomatic?

EP. 8 Protecting bone health for patients receiving Ra-223 + ARPI combination

EP. 8 Protecting bone health for patients receiving Ra-223 + ARPI combination

EP. 9 Ongoing studies of Ra-223–based combinations

EP. 9 Ongoing studies of Ra-223–based combinations

EP. 10 Ongoing studies of Ra- 223–based combinations

EP. 10 Ongoing studies of Ra- 223–based combinations

What were the key efficacy findings from the PEACE-3 study? How do you interpret and think about the results (eg, rPFS, OS)?

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