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Opinion|Videos|November 4, 2024

Current Practices in B7-H3 Testing

Joshua K. Sabari, MD, discusses whether individual B7-H3 analysis is available at his institution, noting that, if it is, he obtains IHC for both PD-L1 and B7-H3 expression levels in all patients with SCLC. If B7-H3 testing becomes available, he would consider adding it to the biomarker assay, particularly at the time of diagnosis or recurrence.

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Video content above is prompted by the following:

  • Is individual B7-H3 analysis currently available at your institution ?
    If so, do you obtain IHC for both PD-L1 and B7-H3 expression levels in all your patients with SCLC?
    If not, when IHC and/or PC does become available for B7-H3 testing, would you consider adding it to your biomarker assay?
    o At which stage of disease

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