HCC

Later Line Therapeutic Decisions in Metastatic HCC

Later Line Therapeutic Decisions in Metastatic HCC

Current guidelines recommend waiting 6 months before resecting a large hepatocellular adenoma to prevent a transformation to a malignant tumor; however, a recent study suggests that waiting longer could benefit some patients.

Tim F. Greten, MD, discusses the evolving role of immunotherapy in HCC.

Nivolumab (Opdivo) demonstrated promise as a second-line therapy for patients with hepatocellular carcinoma (HCC), according to results of the CheckMate-040 trial presented at the 2017 International Liver Congress.

An overview of FDA news that happened in April.

Regorafenib has been approved by the FDA as a second-line treatment for patients with unresectable hepatocellular carcinoma who have previously received sorafenib.

Amit Singal, MD, discusses the recent successes in the HCC treatment landscape and the challenges that still remain.

According to an assessment of a large global dataset reported at the 2017 International Liver Congress, log₁₀ alpha fetoprotein level in the blood directly corresponded to the years of posttreatment survival in patients with hepatocellular carcinoma.

Patients with advanced hepatocellular carcinoma who were previously treated with sorafenib had long-term responses to nivolumab of more than 1 year.

In patients with hepatocellular carcinoma, liver-targeting treatment with selective internal radiation therapy more effectively controlled liver tumor progression and was better tolerated, but the therapy did not improve rates of overall or progression-free survival over sorafenib.